In view of the advances in medical therapy across the spectrum of cardiovascular diseases, the Task Force has designated the term guideline-directed medical therapy (GDMT) to represent optimal medical therapy as defined by ACCF/AHA guideline-recommended therapies (primarily Class I). This new term, GDMT, will be used herein and throughout all future guidelines.

The New York Heart Association (NYHA) Functional Classification provides a simple way of classifying the extent of heart failure. It places patients in one of four categories based on how much These include use of the New York Heart Association (NYHA) classification to grade the severity of functional limitation and patient estimates of how far they are able to walk before they become breathless. The NYHA classification (table 1 1)) is commonly used as a method for functional classification in patients with heart failure. It was INDICATION. ENTRESTO ® is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.. ENTRESTO is usually administered in conjunction with other heart failure therapies, in place of an ACE inhibitor or other ARB. 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. J Am Coll Cardiol 2017;Apr 28:[Epub ahead of print]. An overview of the NYHA heart failure classification. New York Heart Association heart failure classification Published on Sep 7, 2014. 24 Ponrathi Athilingam et al.: Predictive Validity of NYHA and ACC/AHA Classifications of Physical and Cognitive Functioning in Heart Failure The purpose of this secondary analysis is to examine the validity of the NYHA class and ACC/AHA stages of HF to determine HF severity among 90 individuals with